Recombinant human SORBS3 protein
SORBS3 is an SH3 domain-containing adaptor protein. The presence of SH3 domains play a role in this protein's ability to bind other cytoplasmic molecules and contribute to cystoskeletal organization, cell adhesion and migration, signaling, and gene expression. Multiple transcript variants encoding different isoforms have been found for this gene. Recombinant human SORBS3 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.
Product Specifications
Product Name Alternative
Vinexin, SCAM-1, SCAM1, SH3D4
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.25 mg/mL (determined by Bradford assay)
Purity
> 90% by SDS-PAGE
Molecular Weight
39.1 kDa (352aa) confirmed by MALDI-TOF
Additionnal Information
References & Citations
Kioka N. et al. (1999) J Cell Biol. 144:59-69; ; Akamatsu M. et al. (1999) J Biol Chem. 274:35933-35937.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 20% glycerol, 1mM DTT
Scientific Category
Signal Transduction
NCBI Accession Number
NP_001018003
Uniprot Accession Number
O60504
Species
Human
AA Sequence
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