Recombinant human SORBS3 protein

SORBS3 is an SH3 domain-containing adaptor protein. The presence of SH3 domains play a role in this protein's ability to bind other cytoplasmic molecules and contribute to cystoskeletal organization, cell adhesion and migration, signaling, and gene expression. Multiple transcript variants encoding different isoforms have been found for this gene. Recombinant human SORBS3 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.

Product Specifications

Product Name Alternative

Vinexin, SCAM-1, SCAM1, SH3D4

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.25 mg/mL (determined by Bradford assay)

Purity

> 90% by SDS-PAGE

Molecular Weight

39.1 kDa (352aa) confirmed by MALDI-TOF

Additionnal Information

SORBS3, Vinexin, SCAM-1, SCAM1, SH3D4, ATGP2504-10 µg, ATGP2504-20 µg, ATGP2504-50 µg, ATGP2504-100 µg, ATGP2504-250 µg, ATGP2504-500 µg, ATGP2504-1 mg, ATGP2504-10, ATGP2504-20, ATGP2504-50, ATGP2504-100, ATGP2504-250, ATGP2504-500, ATGP2504-1

References & Citations

Kioka N. et al. (1999) J Cell Biol. 144:59-69; ; Akamatsu M. et al. (1999) J Biol Chem. 274:35933-35937.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 20% glycerol, 1mM DTT

Scientific Category

Signal Transduction

NCBI Accession Number

NP_001018003

Uniprot Accession Number

O60504

Species

Human

AA Sequence

MADGGSP FLGRRDFVYP SSTRDPSASN GGGSPARREE KKRKAARLKF DFQAQSPKEL TLQKGDIVYI HKEVDKNWLE GEHHGRLGIF PANYVEVLPA DEIPKPIKPP TYQVLEYGEA VAQYTFKGDL EVELSFRKGE HICLIRKVNE NWYEGRITGT GRQGIFPASY VQVSREPRLR LCDDGPQLPT SPRLTAAARS ARHPSSPSAL RSPADPIDLG GQTSPRRTGF SFPTQEPRPQ TQNLGTPGPA LSHSRGPSHP LDLGTSSPNT SQIHWTPYRA MYQYRPQNED ELELREGDRV DVMQQCDDGW FVGVSRRTQK FGTFPGNYVA PV