Recombinant human Cathepsin W protein
The protein encoded by this gene, a member of the peptidase C1 family, is a cysteine proteinase that may have a specific function in the mechanism or regulation of T-cell cytolytic activity. The encoded protein is found associated with the membrane inside the endoplasmic reticulum of natural killer and cytotoxic T-cells. Expression of this gene is up-regulated by interleukin-2. Recombinant human CTSW protein, fused to His-tag at N-terminus, was expressed in E. coli.
Product Specifications
Product Name Alternative
Cathepsin W preproprotein, CTSW, CatW, Lymphopain
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE, Denatured
Concentration
0.5 mg/mL (determined by Bradford assay)
Purity
> 85% by SDS-PAGE
Molecular Weight
42 kDa (378aa)
Additionnal Information
References & Citations
Raab AK, Monkemuller K, et al. (2011) . Biol Chem. 392 (12) :1167-72. ; ; Stoeckle C, Gouttefangeas C, et al. (2009) . Exp Hematol. 37 (2) :266-75.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol
Scientific Category
Immunology
NCBI Accession Number
NP_001326
Uniprot Accession Number
P56202
Species
Human
AA Sequence
Frequently Asked Questions
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