Recombinant human NKp44/NCR2 protein
NCR2 belongs to the natural cytotoxicity receptor (NCR) family and contains 1 Ig-like (immunoglobulin-like) domain. This protein interacts with TYROBP/DAP12 and is selectively expressed by activated NK cells and by in vitro cultured (i. e. activated) TCRg/d lymphoid cells. NCR2 is a cytotoxicity-activating receptor that may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis. Recombinant human NKP44 protein, fused to His-tag at N-terminus, was expressed in E. coli
Product Specifications
Product Name Alternative
Natural cytotoxicity triggering receptor 2 isoform 1, CD336, LY95, NK-p44 NKP44
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE, Denatured
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 80% by SDS-PAGE
Molecular Weight
15 kDa (133aa)
Additionnal Information
References & Citations
Vitale M, Bottino C et al. (1998) J Exp Med. 15; ;187 (12) :2065-72.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 0.4M urea
Scientific Category
Signal Transduction
NCBI Accession Number
NP_004819.2
Uniprot Accession Number
O95944
Species
Human
AA Sequence
MGSSHHHHHH SSGLVPRGSH MSQAQSKAQV LQSVAGQTLT VRCQYPPTGS LYEKKGWCKE ASALVCIRLV TSSKPRTMAW TSRFTIWDDP DAGFFTVTMT DLREEDSGHY WCRIYRPSDN SVSKSVRFYL VVS
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
WDR5, NT (WDR5, BIG3, WD repeat-containing protein 5, BMP2-induced 3-kb gene protein) (Azide free) (HRP)
WDR5, NT (WDR5, BIG3, WD repeat-containing protein 5, BMP2-induced 3-kb gene protein) (Azide free) (HRP)