Recombinant human Neurogenin-3 protein

NEuROG3 is a basic helix-loop-helix (bHLH) transcription factor involved in neurogenesis. The protein likely acts as a heterodimer with another bHLH protein. Defects in this gene are a cause of congenital malabsorptive diarrhea 4 (DIAR4) . Recombinant human NeuroG3 protein, fused to His-tag at N-terminus, was expressed in E. coli

Product Specifications

Product Name Alternative

Neurogenin 3, Atoh5, bHLHa7, Math4B, ngn3

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE, Denatured

Concentration

0.25 mg/mL (determined by Bradford assay)

Purity

> 85% by SDS-PAGE

Molecular Weight

25.1 kDa (234aa)

Additionnal Information

Neurogenin3, Neurogenin 3, Atoh5, bHLHa7, Math4B, ngn3, ATGP2498-10 µg, ATGP2498-20 µg, ATGP2498-50 µg, ATGP2498-100 µg, ATGP2498-250 µg, ATGP2498-500 µg, ATGP2498-1 mg, ATGP2498-10, ATGP2498-20, ATGP2498-50, ATGP2498-100, ATGP2498-250, ATGP2498-500, ATGP2498-1

References & Citations

Wang J., Cortina G. et al. (2006) N. Engl. J. Med. 355:270-280

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 0.4M urea

Scientific Category

Stem Cell

NCBI Accession Number

AAH74938.1

Uniprot Accession Number

Q9Y4Z2

Species

Human

AA Sequence

MGSSHHHHHH SSGLVPRGSH MTPQPSGAPT VQVTRETERS FPRASEDEVT CPTSAPPSPT RTRGNCAEAE EGGCRGAPRK LRARRGGRSR PKSELALSKQ RRSRRKKAND RERNRMHNLN SALDALRGVL PTFPDDAKLT KIETLRFAHN YIWALTQTLR IADHSLYALE PPAPHCGELG SPGGSPGDWG SLYSPVSQAG SLSPAASLEE RPGLLGATSS ACLSPGSLAF SDFL