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Recombinant human MIA protein

MIA belongs to the MIA/OTOR family and contains 1 SH3 domain. This protein elicits growth inhibition on melanoma cells in vitro as well as some other neuroectodermal tumors, including gliomas. Recombinant human MIA protein, fused to His-tag at N-terminus, was expressed in E. coli

Product Specifications

Product Name Alternative

Melanoma inhibitory activity, CD-RAP

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE, Denatured

Concentration

0.25 mg/mL (determined by Bradford assay)

Purity

> 90% by SDS-PAGE

Molecular Weight

14.4 kDa (128aa)

Additionnal Information

MIA, Melanoma inhibitory activity, CD-RAP, ATGP2497-10 µg, ATGP2497-20 µg, ATGP2497-50 µg, ATGP2497-100 µg, ATGP2497-250 µg, ATGP2497-500 µg, ATGP2497-1 mg, ATGP2497-10, ATGP2497-20, ATGP2497-50, ATGP2497-100, ATGP2497-250, ATGP2497-500, ATGP2497-1

References & Citations

Blesch A, Bosserhoff AK, et al. (1994) Cancer Res 54 (21) : 5695-701.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 0.4M urea

Scientific Category

Cancer

NCBI Accession Number

NP_006524.1

Uniprot Accession Number

Q16674

Species

Human

AA Sequence

MGSSHHHHHH SSGLVPRGSH MGPMPKLADR KLCADQECSH PISMAVALQD YMAPDCRFLT IHRGQVVYVF SKLKGRGRLF WGGSVQGDYY GDLAARLGYF PSSIVREDQT LKPGKVDVKT DKWDFYCQ

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