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Recombinant human CEND1 protein

CEND1, as known as BM88, is a neuron-specific protein. It participates in cell cycle control and neuronal differentiation mechanisms during neonatal SVZ neurogenesis and becomes crucial for the transition from neuroblasts to mature neurons when reaching high levels. The similar protein in pig enhances neuroblastoma cell differentiation in vitro and may be involved in neuronal differentiation in vivo. Recombinant human CEND1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.

Product Specifications

Product Name Alternative

Cell cycle exit and neuronal differentiation protein 1, Cell cycle exit and neuronal differentiation protein 1, BM88

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

1 mg/mL (determined by BCA assay)

Purity

> 85% by SDS-PAGE

Molecular Weight

15kDa (148aa) confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)

Additionnal Information

CEND1, Cell cycle exit and neuronal differentiation protein 1, Cell cycle exit and neuronal differentiation protein 1, BM88, ATGP2494-10 µg, ATGP2494-20 µg, ATGP2494-50 µg, ATGP2494-100 µg, ATGP2494-250 µg, ATGP2494-500 µg, ATGP2494-1 mg, ATGP2494-10, ATGP2494-20, ATGP2494-50, ATGP2494-100, ATGP2494-250, ATGP2494-500, ATGP2494-1

References & Citations

Makri G. et al. (2010) Stem Cells. 28:127-139; ; Katsimpardi L. et al. (2008) Stem Cells. 26:1796-1807.;

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol

Scientific Category

Neuroscience

NCBI Accession Number

NP_057648

Uniprot Accession Number

Q8N111

Species

Human

AA Sequence

MESRGKS ASSPKPDTKV PQVTTEAKVP PAADGKAPLT KPSKKEAPAE KQQPPAAPTT APAKKTSAKA DPALLNNHSN LKPAPTVPSS PDATPEPKGP GDGAEEDEAA SGGPGGRGPW SCENFNPL

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