Recombinant human CEND1 protein
CEND1, as known as BM88, is a neuron-specific protein. It participates in cell cycle control and neuronal differentiation mechanisms during neonatal SVZ neurogenesis and becomes crucial for the transition from neuroblasts to mature neurons when reaching high levels. The similar protein in pig enhances neuroblastoma cell differentiation in vitro and may be involved in neuronal differentiation in vivo. Recombinant human CEND1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.
Product Specifications
Product Name Alternative
Cell cycle exit and neuronal differentiation protein 1, Cell cycle exit and neuronal differentiation protein 1, BM88
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
1 mg/mL (determined by BCA assay)
Purity
> 85% by SDS-PAGE
Molecular Weight
15kDa (148aa) confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)
Additionnal Information
References & Citations
Makri G. et al. (2010) Stem Cells. 28:127-139; ; Katsimpardi L. et al. (2008) Stem Cells. 26:1796-1807.;
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol
Scientific Category
Neuroscience
NCBI Accession Number
NP_057648
Uniprot Accession Number
Q8N111
Species
Human
AA Sequence
MESRGKS ASSPKPDTKV PQVTTEAKVP PAADGKAPLT KPSKKEAPAE KQQPPAAPTT APAKKTSAKA DPALLNNHSN LKPAPTVPSS PDATPEPKGP GDGAEEDEAA SGGPGGRGPW SCENFNPL
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