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Recombinant human PCSK1N protein

Members of the subtilisin-like proprotein convertase family process latent precursor proteins into their biologically active products. PCSK1N functions as an inhibitor of prohormone convertase 1, which regulates the proteolytic cleavage of neuroendocrine peptide precursors. Recombinant human PCSK1N protein, fused to His-tag at N-terminus, was expressed in E. coli.

Product Specifications

Product Name Alternative

ProSAAS precursor, ProSAAS precursor, Proprotein convertase subtilisin/kexin type 1 inhibitor, PROSAAS; SAAS

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE, Denatured

Concentration

0.25 mg/mL (determined by Bradford assay)

Purity

> 85% by SDS-PAGE

Molecular Weight

26.6 kDa (251aa)

Additionnal Information

PCSK1N, ProSAAS precursor, ProSAAS precursor, Proprotein convertase subtilisin/kexin type 1 inhibitor, PROSAAS; SAAS, ATGP2488-10 µg, ATGP2488-20 µg, ATGP2488-50 µg, ATGP2488-100 µg, ATGP2488-250 µg, ATGP2488-500 µg, ATGP2488-1 mg, ATGP2488-10, ATGP2488-20, ATGP2488-50, ATGP2488-100, ATGP2488-250, ATGP2488-500, ATGP2488-1

References & Citations

Fricker L., McKinzie A.A.. et al. (2000) . J. Neurosci. 20:639-648

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing , 10% glycerol, 0.4M urea

Scientific Category

Metabolism

NCBI Accession Number

NP_037403

Uniprot Accession Number

Q9UHG2

Species

Human

AA Sequence

MGSSHHHHHH SSGLVPRGSH MGSMARPVKE PRGLSAASPP LAETGAPRRF RRSVPRGEAA GAVQELARAL AHLLEAERQE RARAEAQEAE DQQARVLAQL LRVWGAPRNS DPALGLDDDP DAPAAQLARA LLRARLDPAA LAAQLVPAPV PAAALRPRPP VYDDGPAGPD AEEAGDETPD VDPELLRYLL GRILAGSADS EGVAAPRRLR RAADHDVGSE LPPEGVLGAL LRVKRLETPA PQVPARRLLP P
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