Recombinant human B7-H4 protein
The VCTN1 is a protein belonging to the B7 costimulatory protein family. Proteins in this family are present on the surface of antigen-presenting cells and interact with ligand bound to receptors on the surface of T cells. Studies have shown that high levels of the encoded protein has been correlated with tumor progression. A pseudogene of this gene is located on chromosome 20. Multiple transcript variants encoding different isoforms have been found for this gene. Recombinant human VTCN1 protein, fused to His-tag at N-terminus, was expressed in E. coli.
Product Specifications
Product Name Alternative
V-set domain containing T cell activation inhibitor 1, B7-H4, B7h.5, B7H4, B7S1, B7X, PRO1291, RP11-229A19.4, VCTN1
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE, Denatured
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 90% by SDS-PAGE
Molecular Weight
28.2 kDa (258aa)
Additionnal Information
References & Citations
Fauci, J.M., et al. (2012) Gynecol. Oncol. 127 (2), 420-425; ; Galazka, K., et al. (2012) Am. J. Reprod. Immunol. 68 (1), 85-93;
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.4M uREA, 10% glycerol
Scientific Category
Cancer
NCBI Accession Number
NP_078902
Uniprot Accession Number
Q7Z7D3
Species
Human
AA Sequence
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