Recombinant human HSFY1 protein

HSFY1 is a member of the heat shock factor (HSF) family of transcriptional activators for heat shock proteins. This gene is a candidate gene for azoospermia, since it localizes to a region of chromosome Y that is sometimes deleted in infertile males. The genome has two identical copies of this gene within a palindromic region; this record represents the more centromeric copy. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Recombinant human HSFY1 protein, fused to His-tag at N-terminus, was expressed in E. coli.

Product Specifications

Product Name Alternative

Heat shock transcription factor Y-linked isoform 1, Heat shock transcription factor, Y-linked isoform 1, Heat shock transcription factor, Y-linked 1, HSF2L, HSFY

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE, Denatured

Concentration

1 mg/mL (determined by Bradford assay)

Purity

> 80% by SDS-PAGE

Molecular Weight

47.5 kDa (424aa)

Additionnal Information

HSFY1, Heat shock transcription factor Y-linked isoform 1, Heat shock transcription factor, Y-linked isoform 1, Heat shock transcription factor, Y-linked 1, HSF2L, HSFY, ATGP2475-10 µg, ATGP2475-20 µg, ATGP2475-50 µg, ATGP2475-100 µg, ATGP2475-250 µg, ATGP2475-500 µg, ATGP2475-1 mg, ATGP2475-10, ATGP2475-20, ATGP2475-50, ATGP2475-100, ATGP2475-250, ATGP2475-500, ATGP2475-1

References & Citations

Skaletsky H., Kuroda-Kawaguchi T. et al. (2003) . Nature 423:825-837

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing , 10% glycerol, 0.4M urea

Scientific Category

Signal Transduction

NCBI Accession Number

NP_149099

Uniprot Accession Number

Q96LI6

Species

Human

AA Sequence

MGSSHHHHHH SSGLVPRGSH MGSMAHVSSE TQDVSPKDEL TASEASTRSP LCEHTFPGDS DLRSMIEEHA FQVLSQGSLL ESPSYTVCVS EPDKDDDFLS LNFPRKLWKI VESDQFKSIS WDENGTCIVI NEELFKKEIL ETKAPYRIFQ TDAIKSFVRQ LNLYGFSKIQ QNFQRSAFLA TFLSEEKESS VLSKLKFYYN PNFKRGYPQL LVRVKRRIGV KNASPISTLF NEDFNKKHFR AGANMENHNS ALAAEASEES LFSASKNLNM PLTRESSVRQ IIANSSVPIR SGFPPPSPST SVGPSEQIAT DQHAILNQLT TIHMHSHSTY MQARGHIVNF ITTTTSQYHI ISPLQNGYFG LTVEPSAVPT RYPLVSVNEA PYRNMLPAGN PWLQMPTIAD RSAAPHSRLA LQPSPLDKYH PNYN