Recombinant human MBIP protein
MBIP inhibits the MAP3K12 activity to induce the activation of the JNK/SAPK pathway. This protein is a component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4. Recombinant human MBIP protein, fused to His-tag at N-terminus, was expressed in E. coli
Product Specifications
Product Name Alternative
MAP3K12-binding inhibitory protein 1 isoform 1, MAP3K12 binding inhibitory protein 1
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE, Denatured
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 85% by SDS-PAGE
Molecular Weight
41.7 kDa (367aa)
Additionnal Information
References & Citations
Guelman S., Kozuka K. et al. (2009) . Mol. Cell. Biol. 29:1176-1188
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing , 10% glycerol, 0.4M urea
Scientific Category
Signal Transduction
NCBI Accession Number
NP_057670
Uniprot Accession Number
Q9NS73
Species
Human
AA Sequence
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