Recombinant human PRPSAP2 protein
PRPSAP2 is a protein that associates with the enzyme phosphoribosylpyrophosphate synthetase (PRS) . PRS catalyzes the formation of phosphoribosylpyrophosphate which is a substrate for synthesis of purine and pyrimidine nucleotides, histidine, tryptophan and NAD. PRS exists as a complex with two catalytic subunits and two associated subunits. This gene encodes a non-catalytic associated subunit of PRS. Alternate splicing results in multiple transcript variants. Recombinant human PRPSAP2 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
Phosphoribosyl pyrophosphate synthetase-associated protein 2, PAP41
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.25 mg/mL (determined by Bradford assay)
Purity
> 90% by SDS-PAGE
Molecular Weight
43.3 kDa (392aa) confirmed by MALDI-TOF
Additionnal Information
References & Citations
Katashima, R., et al. (1998) Biochim. Biophys. Acta 1396 (3), 245-250
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 20% glycerol, 1mM DTT
Scientific Category
Epigenomics (Transcription & Translation)
NCBI Accession Number
NP_002758
Uniprot Accession Number
O60256
Species
Human
AA Sequence
Frequently Asked Questions
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