Recombinant human PRPSAP2 protein

PRPSAP2 is a protein that associates with the enzyme phosphoribosylpyrophosphate synthetase (PRS) . PRS catalyzes the formation of phosphoribosylpyrophosphate which is a substrate for synthesis of purine and pyrimidine nucleotides, histidine, tryptophan and NAD. PRS exists as a complex with two catalytic subunits and two associated subunits. This gene encodes a non-catalytic associated subunit of PRS. Alternate splicing results in multiple transcript variants. Recombinant human PRPSAP2 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Phosphoribosyl pyrophosphate synthetase-associated protein 2, PAP41

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.25 mg/mL (determined by Bradford assay)

Purity

> 90% by SDS-PAGE

Molecular Weight

43.3 kDa (392aa) confirmed by MALDI-TOF

Additionnal Information

PRPSAP2, phosphoribosyl pyrophosphate synthetase-associated protein 2, PAP41, ATGP2461-10 µg, ATGP2461-20 µg, ATGP2461-50 µg, ATGP2461-100 µg, ATGP2461-250 µg, ATGP2461-500 µg, ATGP2461-1 mg, ATGP2461-10, ATGP2461-20, ATGP2461-50, ATGP2461-100, ATGP2461-250, ATGP2461-500, ATGP2461-1

References & Citations

Katashima, R., et al. (1998) Biochim. Biophys. Acta 1396 (3), 245-250

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 20% glycerol, 1mM DTT

Scientific Category

Epigenomics (Transcription & Translation)

NCBI Accession Number

NP_002758

Uniprot Accession Number

O60256

Species

Human

AA Sequence

MFCVTPP ELETKMNITK GGLVLFSANS NSSCMELSKK IAERLGVEMG KVQVYQEPNR ETRVQIQESV RGKDVFIIQT VSKDVNTTIM ELLIMVYACK TSCAKSIIGV IPYFPYSKQC KMRKRGSIVS KLLASMMCKA GLTHLITMDL HQKEIQGFFN IPVDNLRASP FLLQYIQEEI PDYRNAVIVA KSPASAKRAQ SFAERLRLGI AVIHGEAQDA ESDLVDGRHS PPMVRSVAAI HPSLEIPMLI PKEKPPITVV GDVGGRIAII VDDIIDDVDS FLAAAETLKE RGAYKIFVMA THGLLSSDAP RRIEESAIDE VVVTNTIPHE VQKLQCPKIK TVDISMILSE AIRRIHNGES MSYLFRNIGL DD