Recombinant human FAAH2 protein

FAAH2 is a fatty acid amide hydrolase that shares a conserved protein motif with the amidase signature family of enzymes. The encoded enzyme is able to catalyze the hydrolysis of a broad range of bioactive lipids, including those from the three main classes of fatty acid amides; N-acylethanolamines, fatty acid primary amides and N-acyl amino acids. This enzyme has a preference for monounsaturated acyl chains as a substrate. Recombinant human FAAH2 protein, fused to His-tag at N-terminus, was expressed in E. coli.

Product Specifications

Product Name Alternative

Fatty acid amide hydrolase 2, AMDD, Amidase domain containing, Anandamide amidohydrolase 2, Oleamide hydrolase 2

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE, Denatured

Concentration

1 mg/mL (determined by Bradford assay)

Purity

> 80% by SDS-PAGE

Molecular Weight

57.4 kDa (524aa)

Additionnal Information

AMDD, Amidase domain containing, Anandamide amidohydrolase 2, FAA, Fatty acid amide hydrolase 2, Fatty-acid amide hydrolase 2, Oleamide hydrolase 2, ATGP2459-10 µg, ATGP2459-20 µg, ATGP2459-50 µg, ATGP2459-100 µg, ATGP2459-250 µg, ATGP2459-500 µg, ATGP2459-1 mg, ATGP2459-010, ATGP2459-020, ATGP2459-050, ATGP2459-100, ATGP2459-250, ATGP2459-500, ATGP2459-01M

References & Citations

Wei B.Q., Mikkelsen T.S.. et al. (2006) . J. Biol. Chem. 281:36569-36578

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing , 10% glycerol, 0.4M urea

Scientific Category

Metabolism

NCBI Accession Number

NP_777572

Uniprot Accession Number

Q6GMR7

Species

Human

AA Sequence

MGSSHHHHHH SSGLVPRGSH MGSGGPKFAS KTPRPVTEPL LLLSGMQLAK LIRQRKVKCI DVVQAYINRI KDVNPMINGI VKYRFEEAMK EAHAVDQKLA EKQEDEATLE NKWPFLGVPL TVKEAFQLQG MPNSSGLMNR RDAIAKTDAT VVALLKGAGA IPLGITNCSE LCMWYESSNK IYGRSNNPYD LQHIVGGSSG GEGCTLAAAC SVIGVGSDIG GSIRMPAFFN GIFGHKPSPG VVPNKGQFPL AVGAQELFLC TGPMCRYAED LAPMLKVMAG PGIKRLKLDT KVHLKDLKFY WMEHDGGSFL MSKVDQDLIM TQKKVVVHLE TILGASVQHV KLKKMKYSFQ LWIAMMSAKG HDGKEPVKFV DLLGDHGKHV SPLWELIKWC LGLSVYTIPS IGLALLEEKL RYSNEKYQKF KAVEESLRKE LVDMLGDDGV FLYPSHPTVA PKHHVPLTRP FNFAYTGVFS ALGLPVTQCP LGLNAKGLPL GIQVVAGPFN DHLTLAVAQY LEKTFGGWVC PGKF