Recombinant human CENPP protein

Centromere protein P, also known as CENPP, is component of the CENPA-CAD (nucleosome distal) complex, a complex recruited to centromeres which is involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation. This protein may be involved in incorporation of newly synthesized CENPA into centromeres via its interaction with the CENPA-NAC complex. Recombinant human CENPP protein, fused to His-tag at N-terminus, was expressed in E. coli.

Product Specifications

Product Name Alternative

Centromere protein P, CENP-P, RP11-19J3.3

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE, Denatured

Concentration

1 mg/mL (determined by Bradford assay)

Purity

> 85% by SDS-PAGE

Molecular Weight

35.3 kDa (308aa)

Additionnal Information

CENPP, Centromere protein P, CENP-P, RP11-19J3.3, ATGP2448-10 µg, ATGP2448-20 µg, ATGP2448-50 µg, ATGP2448-100 µg, ATGP2448-250 µg, ATGP2448-500 µg, ATGP2448-1 mg, ATGP2448-10, ATGP2448-20, ATGP2448-50, ATGP2448-100, ATGP2448-250, ATGP2448-500, ATGP2448-1

References & Citations

Okada M., et al. (2006) Nat. Cell Biol. 8:446-457; ; Foltz D.R., et al. (2006) Nat. Cell Biol. 8:458-469

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol

Scientific Category

Epigenomics (Transcription & Translation)

NCBI Accession Number

NP_001012267

Uniprot Accession Number

Q6IPU0

Species

Human

AA Sequence

MDAELAEVRA LQAEIAALRR ACEDPPAPWE EKSRVQKSFQ AIHQFNLEGW KSSKDLKNQL GHLESELSFL STLTGINIRN HSKQTEDLTS TEMTEKSIRK VLQRHRLSGN CHMVTFQLEF QILEIQNKER LSSAVTDLNI IMEPTECSEL SEFVSRAEER KDLFMFFRSL HFFVEWFEYR KRTFKHLKEK YPDAVYLSEG PSSCSMGIRS ASRPGFELVI VWRIQIDEDG KVFPKLDLLT KVPQRALELD KNRAIETAPL SFRTLVGLLG IEAALESLIK SLCAEENN