Recombinant human CENPP protein
Centromere protein P, also known as CENPP, is component of the CENPA-CAD (nucleosome distal) complex, a complex recruited to centromeres which is involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation. This protein may be involved in incorporation of newly synthesized CENPA into centromeres via its interaction with the CENPA-NAC complex. Recombinant human CENPP protein, fused to His-tag at N-terminus, was expressed in E. coli.
Product Specifications
Product Name Alternative
Centromere protein P, CENP-P, RP11-19J3.3
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE, Denatured
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 85% by SDS-PAGE
Molecular Weight
35.3 kDa (308aa)
Additionnal Information
References & Citations
Okada M., et al. (2006) Nat. Cell Biol. 8:446-457; ; Foltz D.R., et al. (2006) Nat. Cell Biol. 8:458-469
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol
Scientific Category
Epigenomics (Transcription & Translation)
NCBI Accession Number
NP_001012267
Uniprot Accession Number
Q6IPU0
Species
Human
AA Sequence
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