Recombinant human FANK1 protein

FANK1 was localized in the nuclei of the same cells within the seminiferous epithelium. Consistent with its nuclear localization, a gene ontology analysis suggests that FANK1 has a DNA binding activity and thus may function as a transcription factor. Given the highly restricted expression of FANK1, it may have a role in regulating gene expression in the transition from the meiotic phase to the haploid phase during spermatogenesis. Recombinant human FANK1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Fibronectin type 3 and ankyrin repeat domains protein 1, HSD13

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

1 mg/mL (determined by Bradford assay)

Purity

> 85% by SDS-PAGE

Molecular Weight

40.7 kDa (368aa) confirmed by MALDI-TOF

Additionnal Information

FANK1, fibronectin type 3 and ankyrin repeat domains protein 1, HSD13, ATGP2428-10 µg, ATGP2428-20 µg, ATGP2428-50 µg, ATGP2428-100 µg, ATGP2428-250 µg, ATGP2428-500 µg, ATGP2428-1 mg, ATGP2428-10, ATGP2428-20, ATGP2428-50, ATGP2428-100, ATGP2428-250, ATGP2428-500, ATGP2428-1

References & Citations

Bulfone, A., et al. (2004) Gene Expr. Patterns 4 (3), 297-301

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 20% glycerol

Scientific Category

Development

NCBI Accession Number

NP_660278.3

Uniprot Accession Number

Q8TC84

Species

Human

AA Sequence

MEPQKIM PPSKPHPPVV GKVTHHSIEL YWDLEKKAKR QGPQEQWFRF SIEEEDPKMH TYGIIYTGYA TKHVVEGLEP RTLYRFRLKV TSPSGECEYS PLVSVSTTRE PISSEHLHRA VSVNDEDLLV RILQGGRVKV DVPNKFGFTA LMVAAQKGYT RLVKILVSNG TDVNLKNGSG KDSLMLACYA GHLDVVKYLR RHGASWQARD LGGCTALHWA ADGGHCSVIE WMIKDGCEVD VVDTGSGWTP LMRVSAVSGN QRVASLLIDA GANVNVKDRN GKTPLMVAVL NNHEELVQLL LDKGADASVK NEFGKGVLEM ARVFDRQSVV SLLEERKKKQ RPKKSCVC