Recombinant human FANK1 protein
FANK1 was localized in the nuclei of the same cells within the seminiferous epithelium. Consistent with its nuclear localization, a gene ontology analysis suggests that FANK1 has a DNA binding activity and thus may function as a transcription factor. Given the highly restricted expression of FANK1, it may have a role in regulating gene expression in the transition from the meiotic phase to the haploid phase during spermatogenesis. Recombinant human FANK1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
Fibronectin type 3 and ankyrin repeat domains protein 1, HSD13
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 85% by SDS-PAGE
Molecular Weight
40.7 kDa (368aa) confirmed by MALDI-TOF
Additionnal Information
References & Citations
Bulfone, A., et al. (2004) Gene Expr. Patterns 4 (3), 297-301
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 20% glycerol
Scientific Category
Development
NCBI Accession Number
NP_660278.3
Uniprot Accession Number
Q8TC84
Species
Human
AA Sequence
Frequently Asked Questions
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