Recombinant human CDK16 protein

Cyclin-dependent kinase 16 isoform 1, also known as CDK16, belong to the CDK family of serine/threonine protein kinases. These proteins have a core kinase domain flanked by unique amino- and carboxy-terminal domains. CDK proteins are known to regulate the cell cycle. CDK16, which is expressed primarily in mammalian brain, interacts with a variety of proteins, and is thought to be part of a multiple signal transduction cascade. Recombinant human CDK16 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Cyclin-dependent kinase 16 isoform 1, Cyclin-dependent kinase 16 isoform 1, PCTAIRE, PCTAIRE1, PCTGAIRE, PCTK1

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

1 mg/mL (determined by Bradford assay)

Purity

> 95% by SDS-PAGE

Molecular Weight

41.1 kDa (362aa) confirmed by MALDI-TOF

Additionnal Information

CDK16, Cyclin-dependent kinase 16 isoform 1, Cyclin-dependent kinase 16 isoform 1, PCTAIRE, PCTAIRE1, PCTGAIRE, PCTK1, ATGP2423-10 µg, ATGP2423-20 µg, ATGP2423-50 µg, ATGP2423-100 µg, ATGP2423-250 µg, ATGP2423-500 µg, ATGP2423-1 mg, ATGP2423-10, ATGP2423-20, ATGP2423-50, ATGP2423-100, ATGP2423-250, ATGP2423-500, ATGP2423-1

References & Citations

Cheng K., et al. (2002) J Biol Chem. 277:31988-31993.; ; Meyerson M., et al. (1992) EMBO J. 118:2909-2917.;

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 10% glycerol

Scientific Category

Signal Transduction

NCBI Accession Number

NP_006192

Uniprot Accession Number

Q00536

Species

Human

AA Sequence

GFGKLET YIKLDKLGEG TYATVYKGKS KLTDNLVALK EIRLEHEEGA PCTAIREVSL LKDLKHANIV TLHDIIHTEK SLTLVFEYLD KDLKQYLDDC GNIINMHNVK LFLFQLLRGL AYCHRQKVLH RDLKPQNLLI NERGELKLAD FGLARAKSIP TKTYSNEVVT LWYRPPDILL GSTDYSTQID MWGVGCIFYE MATGRPLFPG STVEEQLHFI FRILGTPTEE TWPGILSNEE FKTYNYPKYR AEALLSHAPR LDSDGADLLT KLLQFEGRNR ISAEDAMKHP FFLSLGERIH KLPDTTSIFA LKEIQLQKEA SLRSSSMPDS GRPAFRVVDT EF