Recombinant human JMJD7 protein

JMJD7, also known as JmjC domain-containing protein 7, belongs to the JMJD family. While several JMJD proteins have been identified as being involved in chromatin regulation, histone demethylation and development, the function of JMJD7 has not been identified. It was initially thought to be a novel splice form of the phospholipase PLA2G4B which is located downstream of JMJD7 as most tissues express a read-through transcript of the two genes. Recombinant human JMJD7 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

JmjC domain-containing protein 7, jumonji domain containing 7, Jumonji domain-containing protein 7

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

1 mg/mL (determined by Bradford assay)

Purity

> 90% by SDS-PAGE

Molecular Weight

38.3 kDa (339aa) confirmed by MALDI-TOF

Additionnal Information

JMJD7, JmjC domain-containing protein 7, jumonji domain containing 7, Jumonji domain-containing protein 7, ATGP2420-10 µg, ATGP2420-20 µg, ATGP2420-50 µg, ATGP2420-100 µg, ATGP2420-250 µg, ATGP2420-500 µg, ATGP2420-1 mg, ATGP2420-10, ATGP2420-20, ATGP2420-50, ATGP2420-100, ATGP2420-250, ATGP2420-500, ATGP2420-1

References & Citations

Takeuchi T. et al. (2006) Dev. Dyn. 235:2449-2459.; ; Clissold PM. et al. (2001) Trends Biochem. Sci.. 26:7-9;

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol 0.1M NaCl

Scientific Category

Other

NCBI Accession Number

NP_001108104

Uniprot Accession Number

P0C870

Species

Human

AA Sequence

MAEAALE AVRSELREFP AAARELCVPL AVPYLDKPPT PLHFYRDWVC PNRPCIIRNA LQHWPALQKW SLPYFRATVG STEVSVAVTP DGYADAVRGD RFMMPAERRL PLSFVLDVLE GRAQHPGVLY VQKQCSNLPS ELPQLLPDLE SHVPWASEAL GKMPDAVNFW LGEAAAVTSL HKDHYENLYC VVSGEKHFLF HPPSDRPFIP YELYTPATYQ LTEEGTFKVV DEEAMEKVPW IPLDPLAPDL ARYPSYSQAQ ALRCTVRAGE MLYLPALWFH HVQQSQGCIA VNFWYDMEYD LKYSYFQLLD SLTKASGLD