Recombinant human EXOSC4 protein
EXOSC4, also known as fetuin-A, belongs to the fetuin class of plasma binding proteins. It is involved in several functions, such as endocytosis, brain development and the formation of bone tissue. It is commonly present in the cortical plate of the immature cerebral cortex and bone marrow hemopoietic matrix, and it has been postulated that it participates in the development of the tissues. It forms soluble complexes with calcium and phosphate and thus is a carrier of otherwise insoluble calcium phosphate. Recombinant human EXOSC4 protein, fused to His-tag at N-terminus, was expressed in E. coli.
Product Specifications
Product Name Alternative
Exosome complex component RRP41, Exosome complex component RRP41, hRrp41p, p12A, RRP41, RRP41A, Rrp41p, SKI6, Ski6p
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE, Denatured
Concentration
0.5 mg/mL (determined by Bradford assay)
Purity
> 85% by SDS-PAGE
Molecular Weight
28.8 kDa (268aa)
Additionnal Information
References & Citations
Osawa M. et al. (1997) Gene. 196:121-125.; ; Rizzu P. et al. (1995) Cytogenet Cell Genet.. 70:26-28.;
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol 0.4M urea
Scientific Category
Epigenomics (Transcription & Translation)
NCBI Accession Number
NP_061910
Uniprot Accession Number
Q9NPD3
Species
Human
AA Sequence
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