Recombinant human EXOSC4 protein

EXOSC4, also known as fetuin-A, belongs to the fetuin class of plasma binding proteins. It is involved in several functions, such as endocytosis, brain development and the formation of bone tissue. It is commonly present in the cortical plate of the immature cerebral cortex and bone marrow hemopoietic matrix, and it has been postulated that it participates in the development of the tissues. It forms soluble complexes with calcium and phosphate and thus is a carrier of otherwise insoluble calcium phosphate. Recombinant human EXOSC4 protein, fused to His-tag at N-terminus, was expressed in E. coli.

Product Specifications

Product Name Alternative

Exosome complex component RRP41, Exosome complex component RRP41, hRrp41p, p12A, RRP41, RRP41A, Rrp41p, SKI6, Ski6p

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE, Denatured

Concentration

0.5 mg/mL (determined by Bradford assay)

Purity

> 85% by SDS-PAGE

Molecular Weight

28.8 kDa (268aa)

Additionnal Information

EXOSC4, Exosome complex component RRP41, Exosome complex component RRP41, hRrp41p, p12A, RRP41, RRP41A, Rrp41p, SKI6, Ski6p, ATGP2415-10 µg, ATGP2415-20 µg, ATGP2415-50 µg, ATGP2415-100 µg, ATGP2415-250 µg, ATGP2415-500 µg, ATGP2415-1 mg, ATGP2415-10, ATGP2415-20, ATGP2415-50, ATGP2415-100, ATGP2415-250, ATGP2415-500, ATGP2415-1

References & Citations

Osawa M. et al. (1997) Gene. 196:121-125.; ; Rizzu P. et al. (1995) Cytogenet Cell Genet.. 70:26-28.;

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol 0.4M urea

Scientific Category

Epigenomics (Transcription & Translation)

NCBI Accession Number

NP_061910

Uniprot Accession Number

Q9NPD3

Species

Human

AA Sequence

MAGLELL SDQGYRVDGR RAGELRKIQA RMGVFAQADG SAYIEQGNTK ALAVVYGPHE IRGSRARALP DRALVNCQYS SATFSTGERK RRPHGDRKSC EMGLQLRQTF EAAILTQLHP RSQIDIYVQV LQADGGTYAA CVNAATLAVL DAGIPMRDFV CACSAGFVDG TALADLSHVE EAAGGPQLAL ALLPASGQIA LLEMDARLHE DHLERVLEAA AQAARDVHTL LDRVVRQHVR EASILLGD