Recombinant human Snail protein
Snail homolog 1, also known as SNAI1, is involved in the epithelial to mesenchymal transition (EMT) and formation and maintenance of embryonic mesoderm. This protein binds to 3 E-boxes of the E-cadherin gene promoter and represses its transcription. Recombinant human SNAI1 protein, fused to His-tag at N-terminus, was expressed in E. coli
Product Specifications
Product Name Alternative
Snail homolog 1, Snail homolog 1, dJ710H13.1, SLuGH2, SNA, SNAH, SNAIL, SNAIL1
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE, Denatured
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 85% by SDS-PAGE
Molecular Weight
31.5 kDa (287aa)
Additionnal Information
References & Citations
Batlle E., et al. (2000) Nat. Cell Biol. 2:84-89; ; Peinado H., et al. (2005) EMBO J. 24:3446-3458;
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol 0.4M urea
Scientific Category
Development
NCBI Accession Number
NP_005976
Uniprot Accession Number
O95863
Species
Human
AA Sequence
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