Recombinant human Snail protein

Snail homolog 1, also known as SNAI1, is involved in the epithelial to mesenchymal transition (EMT) and formation and maintenance of embryonic mesoderm. This protein binds to 3 E-boxes of the E-cadherin gene promoter and represses its transcription. Recombinant human SNAI1 protein, fused to His-tag at N-terminus, was expressed in E. coli

Product Specifications

Product Name Alternative

Snail homolog 1, Snail homolog 1, dJ710H13.1, SLuGH2, SNA, SNAH, SNAIL, SNAIL1

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE, Denatured

Concentration

1 mg/mL (determined by Bradford assay)

Purity

> 85% by SDS-PAGE

Molecular Weight

31.5 kDa (287aa)

Additionnal Information

Snail, Snail homolog 1, Snail homolog 1, dJ710H13.1, SLuGH2, SNA, SNAH, SNAIL, SNAIL1, ATGP2413-10 µg, ATGP2413-20 µg, ATGP2413-50 µg, ATGP2413-100 µg, ATGP2413-250 µg, ATGP2413-500 µg, ATGP2413-1 mg, ATGP2413-10, ATGP2413-20, ATGP2413-50, ATGP2413-100, ATGP2413-250, ATGP2413-500, ATGP2413-1

References & Citations

Batlle E., et al. (2000) Nat. Cell Biol. 2:84-89; ; Peinado H., et al. (2005) EMBO J. 24:3446-3458;

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol 0.4M urea

Scientific Category

Development

NCBI Accession Number

NP_005976

Uniprot Accession Number

O95863

Species

Human

AA Sequence

MGSSHHHHHH SSGLVPRGSH MGSMPRSFLV RKPSDPNRKP NYSELQDSNP EFTFQQPYDQ AHLLAAIPPP EILNPTASLP MLIWDSVLAP QAQPIAWASL RLQESPRVAE LTSLSDEDSG KGSQPPSPPS PAPSSFSSTS VSSLEAEAYA AFPGLGQVPK QLAQLSEAKD LQARKAFNCK YCNKEYLSLG ALKMHIRSHT LPCVCGTCGK AFSRPWLLQG HVRTHTGEKP FSCPHCSRAF ADRSNLRAHL QTHSDVKKYQ CQACARTFSR MSLLHKHQES GCSGCPR