Recombinant human PIH1D1 protein

PIH1 domain-containing protein 1, also known as PIH1D1, is a phylogenetically conserved protein essential for efficient processing of pre-rRNA through its association with a class of small nucleolar RNAs (snoRNAs) during ribosomal biogenesis. SnoRNAs are associated in ribonucleoprotein particles localized to the nucleolus. PIH1D1 may also function as a novel modulator of apoptosis pathway. Recombinant human PIH1D1 protein, fused to His-tag at N-terminus, was expressed in E. coli.

Product Specifications

Product Name Alternative

PIH1 domain-containing protein 1, NOP17

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE, Denatured

Concentration

0.25 mg/mL (determined by Bradford assay)

Purity

> 85% by SDS-PAGE

Molecular Weight

34.8 kDa (313aa)

Additionnal Information

PIH1D1, PIH1 domain-containing protein 1, NOP17, ATGP2407-10 µg, ATGP2407-20 µg, ATGP2407-50 µg, ATGP2407-100 µg, ATGP2407-250 µg, ATGP2407-500 µg, ATGP2407-1 mg, ATGP2407-10, ATGP2407-20, ATGP2407-50, ATGP2407-100, ATGP2407-250, ATGP2407-500, ATGP2407-1

References & Citations

Gonzales F A., et al. (2005) J Mol Biol. 346:437-455.; ; Granato D C., et al. (2005) FEBS J. 272:4450-4463.;

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol 0.4M urea

Scientific Category

Other

NCBI Accession Number

NP_060386

Uniprot Accession Number

Q9NWS0

Species

Human

AA Sequence

MGSSHHHHHH SSGLVPRGSH MGSMANPKLL GMGLSEAEAI GADSARFEEL LLQASKELQQ AQTTRPESTQ IQPQPGFCIK TNSSEGKVFI NICHSPSIPP PADVTEEELL QMLEEDQAGF RIPMSLGEPH AELDAKGQGC TAYDVAVNSD FYRRMQNSDF LRELVITIAR EGLEDKYNLQ LNPEWRMMKN RPFMGSISQQ NIRSEQRPRI QELGDLYTPA PGRAESGPEK PHLNLWLEAP DLLLAEVDLP KLDGALGLSL EIGENRLVMG GPQQLYHLDA YIPLQINSHE SKAAFHRKRK QLMVAMPLLP VPS