Recombinant human TACO1 protein

TACO1 is a mitochondrial protein that function as a translational activator of mitochondrially-encoded cytochrome c oxidase 1. Mutations in this gene are associated with Leigh syndrome. Recombinant human TACO1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Translational activator of cytochrome c oxidase 1, Translational activator of cytochrome c oxidase 1, CCDC44

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.5 mg/mL (determined by Bradford assay)

Purity

> 95% by SDS-PAGE

Molecular Weight

28.8 kDa (260aa) confirmed by MALDI-TOF

Additionnal Information

TACO1, Translational activator of cytochrome c oxidase 1, Translational activator of cytochrome c oxidase 1, CCDC44, ATGP2400-10 µg, ATGP2400-20 µg, ATGP2400-50 µg, ATGP2400-100 µg, ATGP2400-250 µg, ATGP2400-500 µg, ATGP2400-1 mg, ATGP2400-10, ATGP2400-20, ATGP2400-50, ATGP2400-100, ATGP2400-250, ATGP2400-500, ATGP2400-1

References & Citations

Weraarpachai W., et al. (2009) Nat. Genet. 41:833-837; ; Burkard T.R., et al. (2011) BMC Syst. Biol. 5:17-17;

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol, 1mM DTT

Scientific Category

Metabolism

NCBI Accession Number

NP_057444

Uniprot Accession Number

Q9BSH4

Species

Human

AA Sequence

MGSSHHHHHH SSGLVPRGSH MGSNKWSKVR HIKGPKDVER SRIFSKLCLN IRLAVKEGGP NPEHNSNLAN ILEVCRSKHM PKSTIETALK MEKSKDTYLL YEGRGPGGSS LLIEALSNSS HKCQADIRHI LNKNGGVMAV GARHSFDKKG VIVVEVEDRE KKAVNLERAL EMAIEAGAED VKETEDEEER NVFKFICDAS SLHQVRKKLD SLGLCSVSCA LEFIPNSKVQ LAEPDLEQAA HLIQALSNHE DVIHVYDNIE