Recombinant human NIPSNAP1 protein
NIPSNAP1 is a member of the NipSnap family of proteins that may be involved in vesicular transport. A similar protein in mice inhibits the calcium channel TRPV6, and is also localized to the inner mitochondrial membrane where it may play a role in mitochondrial DNA maintenance. A pseudogene of this gene is located on the short arm of chromosome 17. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Recombinant human NIPSNAP1 protein, fused to His-tag at N-terminus, was expressed in E. coli.
Product Specifications
Product Name Alternative
Nipsnap homolog 1, Nipsnap homolog 1, Translational activator of cytochrome c oxidase 1
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE, Denatured
Concentration
0.5 mg/mL (determined by Bradford assay)
Purity
> 85% by SDS-PAGE
Molecular Weight
35.7 kDa (307aa)
Additionnal Information
References & Citations
Choudhary C., et al. (2009) Science. 325:834-840; ; Burkard T.R., et al. (2011) BMC Syst. Biol. 5:17-17;
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol 0.4M urea
Scientific Category
Signal Transduction
NCBI Accession Number
NP_003625
Uniprot Accession Number
Q9BPW8
Species
Human
AA Sequence
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