Recombinant human GDNFR alpha-3/GFRA3 protein

GFRA3 is a glycosylphosphatidylinositol (GPI) -linked cell surface receptor and a member of the GDNF receptor family. It forms a signaling receptor complex with RET tyrosine kinase receptor and binds the ligand, artemin. Recombinant human GFRA3 protein, fused to His-tag at N-terminus, was expressed in E. coli.

Product Specifications

Product Name Alternative

GDNF family receptor alpha-3, GFRA3, GDNFR3, GFRalpha3

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE, Denatured

Concentration

1 mg/mL (determined by Bradford assay)

Purity

> 85% by SDS-PAGE

Molecular Weight

40.7 kDa (366aa)

Additionnal Information

GFR a3, GDNF family receptor alpha 3, GDNF family receptor alpha 3, GDNF family receptor alpha-3, GDNF receptor alpha-3, GDNFR-alpha-3, GFR-alpha-3, GFRa-3, ATGP2398-10 µg, ATGP2398-20 µg, ATGP2398-50 µg, ATGP2398-100 µg, ATGP2398-250 µg, ATGP2398-500 µg, ATGP2398-1 mg, ATGP2398-10, ATGP2398-20, ATGP2398-50, ATGP2398-100, ATGP2398-250, ATGP2398-500, ATGP2398-1

References & Citations

Baloh R.H., et al. (1998) Neuron. 21:1291-1302; ; Wang X., et al. (2008) Structure. 14:1083-1092;

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol 0.4M urea

Scientific Category

Neuroscience

NCBI Accession Number

NP_001487

Uniprot Accession Number

O60609

Species

Human

AA Sequence

MGSSHHHHHH SSGLVPRGSH MGSDPLPTES RLMNSCLQAR RKCQADPTCS AAYHHLDSCT SSISTPLPSE EPSVPADCLE AAQQLRNSSL IGCMCHRRMK NQVACLDIYW TVHRARSLGN YELDVSPYED TVTSKPWKMN LSKLNMLKPD SDLCLKFAML CTLNDKCDRL RKAYGEACSG PHCQRHVCLR QLLTFFEKAA EPHAQGLLLC PCAPNDRGCG ERRRNTIAPN CALPPVAPNC LELRRLCFSD PLCRSRLVDF QTHCHPMDIL GTCATEQSRC LRAYLGLIGT AMTPNFVSNV NTSVALSCTC RGSGNLQEEC EMLEGFFSHN PCLTEAIAAK MRFHSQLFSQ DWPHPTFAVM AHQNEN