Recombinant human SSSCA1/ZNRD2 protein
SSSCA1 is recognized by a subset of anti-centromere antibodies from patients with scleroderma and/or Sjogren's syndrome. Subcellular localization has not yet been established. Recombinant human SSSCA1 protein, fused to His-tag at N-terminus, was expressed in E. coli.
Product Specifications
Product Name Alternative
Sjoegren syndrome/scleroderma autoantigen 1, Zinc ribbon domain containing 2
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE, Denatured
Concentration
0.5 mg/mL (determined by Bradford assay)
Purity
> 90% by SDS-PAGE
Molecular Weight
23.9 kDa (222aa)
Additionnal Information
References & Citations
Ananthanarayanan, V., et al. (2011) Hum. Pathol. 42 (6), 873-881; ; Lango Allen, H., et al. (2010) Nature 467 (7317), 832-838;
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol 0.4M urea
Scientific Category
Immunology
NCBI Accession Number
NP_006387
Uniprot Accession Number
O60232
Species
Human
AA Sequence
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