Recombinant human APOBEC4 protein

The APOBEC4 is a member of the AID/APOBEC family of polynucleotide (deoxy) cytidine deaminases, which convert cytidine to uridine. Other AID/APOBEC family members are involved in Mrna editing, somatic hypermutation and recombination of immunoglobulin genes, and innate immunity to retroviral infection. Recombinant human APOBEC4 protein, fused to His-tag at N-terminus, was expressed in E. coli.

Product Specifications

Product Name Alternative

Putative C->u-editing enzyme APOBEC-4, C1orf169

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE, Denatured

Concentration

1 mg/mL (determined by Bradford assay)

Purity

> 85% by SDS-PAGE

Molecular Weight

44 kDa (390aa)

Additionnal Information

APOBEC4, putative C->u-editing enzyme APOBEC-4, C1orf169, ATGP2392-10 µg, ATGP2392-20 µg, ATGP2392-50 µg, ATGP2392-100 µg, ATGP2392-250 µg, ATGP2392-500 µg, ATGP2392-1 mg, ATGP2392-10, ATGP2392-20, ATGP2392-50, ATGP2392-100, ATGP2392-250, ATGP2392-500, ATGP2392-1

References & Citations

Prochnow, C., et al. (2009) Sci. China, C, Life Sci. 52 (10), 893-902; ; Rogozin, I.B., et al. (2005) Cell Cycle 4 (9), 1281-1285;

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol 0.4M urea

Scientific Category

Epigenomics (Transcription & Translation)

NCBI Accession Number

NP_982279

Uniprot Accession Number

Q8WW27

Species

Human

AA Sequence

MEPIYEE YLANHGTIVK PYYWLSFSLD CSNCPYHIRT GEEARVSLTE FCQIFGFPYG TTFPQTKHLT FYELKTSSGS LVQKGHASSC TGNYIHPESM LFEMNGYLDS AIYNNDSIRH IILYSNNSPC NEANHCCISK MYNFLITYPG ITLSIYFSQL YHTEMDFPAS AWNREALRSL ASLWPRVVLS PISGGIWHSV LHSFISGVSG SHVFQPILTG RALADRHNAY EINAITGVKP YFTDVLLQTK RNPNTKAQEA LESYPLNNAF PGQFFQMPSG QLQPNLPPDL RAPVVFVLVP LRDLPPMHMG QNPNKPRNIV RHLNMPQMSF QETKDLGRLP TGRSVEIVEI TEQFASSKEA DEKKKKKGKK