Recombinant human PRRX1 protein

Paired related homeobox 1, also known as PRRX1, acts as a transcriptional regulator of muscle creatine kinase (MCK) and so has a role in the establishment of diverse mesodermal muscle types. The protein binds to an A/T-rich element in the muscle creatine enhancer. Recombinant human PRRX1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Paired related homeobox 1, AGOTC, PHOX1, PMX1, PRX-1, PRX1

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.25 mg/mL (determined by Bradford assay)

Purity

> 85% by SDS-PAGE

Molecular Weight

26.9 kDa (241aa) confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)

Additionnal Information

PRRX1, Paired related homeobox 1, AGOTC, PHOX1, PMX1, PRX-1, PRX1, ATGP2368-10 µg, ATGP2368-20 µg, ATGP2368-50 µg, ATGP2368-100 µg, ATGP2368-250 µg, ATGP2368-500 µg, ATGP2368-1 mg, ATGP2368-10, ATGP2368-20, ATGP2368-50, ATGP2368-100, ATGP2368-250, ATGP2368-500, ATGP2368-1

References & Citations

Grueneberg D.A., et al. (1992) Science. 257:1089-1095; ; Sergi C., et al. (2011) Clin. Genet. 79:293-295;

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 50% glycerol, 2mM DTT

Scientific Category

Epigenomics (Transcription & Translation)

NCBI Accession Number

NP_008833

Uniprot Accession Number

P54821

Species

Human

AA Sequence

MTSSYG HVLERQPALG GRLDSPGNLD TLQAKKNFSV SHLLDLEEAG DMVAAQADEN VGEAGRSLLE SPGLTSGSDT PQQDNDQLNS EEKKKRKQRR NRTTFNSSQL QALERVFERT HYPDAFVRED LARRVNLTEA RVQVWFQNRR AKFRRNERAM LANKNASLLK SYSGDVTAVE QPIVPRPAPR PTDYLSWGTA SPYRSSSLPR CCLHEGLHNG F