Recombinant human SLC51B protein
SLC51B, as known as OSTB, is an organic solute transporter subunit. SLC51 is composed of two distinct proteins that must heterodimerize to generate transport activity, but the role of the individual subunits in mediating transport activity is unknown. The results demonstrate that SLC51B is required for both proper trafficking of SLC51A and formation of the functional transport unit, and identify specific residues of SLC51B critical for these processes. Recombinant human SLC51B protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.
Product Specifications
Product Name Alternative
Organic solute transporter subunit beta, OSTB, OSTBETA
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
1 mg/mL (determined by BCA assay)
Purity
> 95% by SDS-PAGE
Molecular Weight
10.7 kDa (95aa) confirmed by MALDI-TOF
Additionnal Information
References & Citations
Christian WV. et al. (2012) J Biol Chem. 287:21233-21243; ; Dawson PA. et al. (2005) J Biol Chem. 280 (8) :6960-6968.;
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol 0.1M NaCl
Scientific Category
Signal Transduction
NCBI Accession Number
NP_849190
Uniprot Accession Number
Q86UW2
Species
Human
AA Sequence
MGSSHHHHHH SSGLVPRGSH MGSRSIQASR KEKMQPPEKE TPEVLHLDEA KDHNSLNNLR ETLLSEKPNL AQVELELKER DVLSVFLPDV PETES
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