Recombinant human GM-CSF R alpha protein

CSF2RA is the alpha subunit of the heterodimeric receptor for colony stimulating factor 2, a cytokine which controls the production, differentiation, and function of granulocytes and macrophages. This protein is a member of the cytokine family of receptors. It is found in the pseudoautosomal region (PAR) of the X and Y chromosomes. Multiple transcript variants encoding different isoforms have been found for this gene, with some of the isoforms being membrane-bound and others being soluble. Recombinant human CSF2RA protein, fused to His-tag at N-terminus, was expressed in E. coli.

Product Specifications

Product Name Alternative

Colony stimulating factor 2 receptor alpha low-affinity, Colony stimulating factor 2 receptor, alpha, low-affinity, CD116, CDw116, CSF2R, GM-CSF-R-alpha, GMCSFR, GMR, SMDP4

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE, Denatured

Concentration

1 mg/mL (determined by Bradford assay)

Purity

> 85% by SDS-PAGE

Molecular Weight

37.2 kDa (324aa)

Additionnal Information

GM-CSF R a, Colony stimulating factor 2 receptor alpha low-affinity, Colony stimulating factor 2 receptor, alpha, low-affinity, CD116, CDw116, CSF2R, GM-CSF-R-alpha, GMCSFR, GMR, SMDP4, ATGP2363-10 µg, ATGP2363-20 µg, ATGP2363-50 µg, ATGP2363-100 µg, ATGP2363-250 µg, ATGP2363-500 µg, ATGP2363-1 mg, ATGP2363-10, ATGP2363-20, ATGP2363-50, ATGP2363-100, ATGP2363-250, ATGP2363-500, ATGP2363-1

References & Citations

Hansen G., et al. (2008) Cell. 134:496-507; ; Suzuki T., et al. (2008) J. Exp. Med. 205:2703-2710

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 0.4M urea

Scientific Category

Stem Cell

NCBI Accession Number

NP_001155003

Uniprot Accession Number

P15509

Species

Human

AA Sequence

MGSSHHHHHH SSGLVPRGSH MGSLIPEKSD LRTVAPASSL NVRFDSRTMN LSWDCQENTT FSKCFLTDKK NRVVEPRLSN NECSCTFREI CLHEGVTFEV HVNTSQRGFQ QKLLYPNSGR EGTAAQNFSC FIYNADLMNC TWARGPTAPR DVQYFLYIRN SKRRREIRCP YYIQDSGTHV GCHLDNLSGL TSRNYFLVNG TSREIGIQFF DSLLDTKKIE RFNPPSNVTV RCNTTHCLVR WKQPRTYQKL SYLDFQYQLD VHRKNTQPGT ENLLINVSGD LENRYNFPSS EPRAKHSVKI RAADVRILNW SSWSEAIEFG SDDG