Recombinant human LRRC59 protein
LRRC59 is required for nuclear import of FGF1, but not that of FGF2. This proein might regulate nuclear import of exogenous FGF1 by facilitating interaction with the nuclear import machinery and by transporting cytosolic FGF1 to, and possibly through, the nuclear pores. Recombinant human LRRC59 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
Leucine-rich repeat-containing protein 59, Leucine rich repeat containing 59, p34, PRO1855
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.25 mg/mL (determined by Bradford assay)
Purity
> 90% by SDS-PAGE
Molecular Weight
30.3 kDa (267aa) confirmed by MALDI-TOF
Additionnal Information
References & Citations
Zhen Y., et al. (2012), Traffic 13:650-664
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 50% glycerol, 2mM DTT, 2mM EDTA
Scientific Category
Signal Transduction
NCBI Accession Number
NP_060979
Uniprot Accession Number
Q96AG4
Species
Human
AA Sequence
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