Recombinant human LRRC59 protein

LRRC59 is required for nuclear import of FGF1, but not that of FGF2. This proein might regulate nuclear import of exogenous FGF1 by facilitating interaction with the nuclear import machinery and by transporting cytosolic FGF1 to, and possibly through, the nuclear pores. Recombinant human LRRC59 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Leucine-rich repeat-containing protein 59, Leucine rich repeat containing 59, p34, PRO1855

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.25 mg/mL (determined by Bradford assay)

Purity

> 90% by SDS-PAGE

Molecular Weight

30.3 kDa (267aa) confirmed by MALDI-TOF

Additionnal Information

LRRC59, Leucine-rich repeat-containing protein 59, Leucine rich repeat containing 59, p34, PRO1855, ATGP2349-10 µg, ATGP2349-20 µg, ATGP2349-50 µg, ATGP2349-100 µg, ATGP2349-250 µg, ATGP2349-500 µg, ATGP2349-1 mg, ATGP2349-10, ATGP2349-20, ATGP2349-50, ATGP2349-100, ATGP2349-250, ATGP2349-500, ATGP2349-1

References & Citations

Zhen Y., et al. (2012), Traffic 13:650-664

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 50% glycerol, 2mM DTT, 2mM EDTA

Scientific Category

Signal Transduction

NCBI Accession Number

NP_060979

Uniprot Accession Number

Q96AG4

Species

Human

AA Sequence

MGSSHHHHHH SSGLVPRGSH MGSMTKAGSK GGNLRDKLDG NELDLSLSDL NEVPVKELAA LPKATILDLS CNKLTTLPSD FCGLTHLVKL DLSKNKLQQL PADFGRLVNL QHLDLLNNKL VTLPVSFAQL KNLKWLDLKD NPLDPVLAKV AGDCLDEKQC KQCANKVLQH MKAVQADQER ERQRRLEVER EAEKKREAKQ RAKEAQEREL RKREKAEEKE RRRKEYDALK AAKREQEKKP KKEANQAPKS KSGSRPRKPP PRKHTRS