Recombinant human OXSM protein

OXSM is a beta-ketoacyl synthetase. The enzyme is required for elongation of fatty acid chains in the mitochondria. Alternatively spliced transcript variants have been described. Recombinant human OXSM protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

3-oxoacyl-ACP synthase mitochondrial, 3-oxoacyl-ACP synthase, mitochondrial, FASN2D, KASI, KS

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.5 mg/mL (determined by Bradford assay)

Purity

> 90% by SDS-PAGE

Molecular Weight

48.1 kDa (455aa) confirmed by MALDI-TOF

Additionnal Information

OXSM, 3-oxoacyl-ACP synthase mitochondrial, 3-oxoacyl-ACP synthase, mitochondrial, FASN2D, KASI, KS, ATGP2347-10 µg, ATGP2347-20 µg, ATGP2347-50 µg, ATGP2347-100 µg, ATGP2347-250 µg, ATGP2347-500 µg, ATGP2347-1 mg, ATGP2347-10, ATGP2347-20, ATGP2347-50, ATGP2347-100, ATGP2347-250, ATGP2347-500, ATGP2347-1

References & Citations

Zhang L., et al (2005) . J. Biol. Chem. 280:12422-12429 (2005)

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol, 1mM DTT

Scientific Category

Metabolism

NCBI Accession Number

NP_060367

Uniprot Accession Number

Q9NWU1

Species

Human

AA Sequence

MGSSHHHHHH SSGLVPRGSH MGSKRKFFGT VPISRLHRRV VITGIGLVTP LGVGTHLVWD RLIGGESGIV SLVGEEYKSI PCSVAAYVPR GSDEGQFNEQ NFVSKSDIKS MSSPTIMAIG AAELAMKDSG WHPQSEADQV ATGVAIGMGM IPLEVVSETA LNFQTKGYNK VSPFFVPKIL VNMAAGQVSI RYKLKGPNHA VSTACTTGAH AVGDSFRFIA HGDADVMVAG GTDSCISPLS LAGFSRARAL STNSDPKLAC RPFHPKRDGF VMGEGAAVLV LEEYEHAVQR RARIYAEVLG YGLSGDAGHI TAPDPEGEGA LRCMAAALKD AGVQPEEISY INAHATSTPL GDAAENKAIK HLFKDHAYAL AVSSTKGATG HLLGAAGAVE AAFTTLACYY QKLPPTLNLD CSEPEFDLNY VPLKAQEWKT EKRFIGLTNS FGFGGTNATL CIAGL