Recombinant human ASB8 protein
Ankyrin repeat and SOCS box containing 8, also known as ASB8, may be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Recombinant human ASB8 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
Ankyrin repeat and SOCS box containing 8, PP14212
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.25 mg/mL (determined by Bradford assay)
Purity
> 90% by SDS-PAGE
Molecular Weight
34.0 kDa (311aa) confirmed by MALDI-TOF
Additionnal Information
References & Citations
Liu Y., et al. (2003) Biochem. Biophys. Res. Commun. 300:972-979; ; Ota T., et al. (2004) Nat. Genet. 36:40-45;
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol, 1mM DTT
Scientific Category
Ubiquitination
NCBI Accession Number
NP_077000
Uniprot Accession Number
Q9H765
Species
Human
AA Sequence
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