Recombinant human JSRP1 protein

JSRP1 is involved in excitation-contraction coupling at the sarcoplasmic reticulum. The protein can interact with CACNA1S, CACNB1, and calsequestrin to help regulate calcium influx and efflux in skeletal muscle. Recombinant human JSRP1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Junctional sarcoplasmic reticulum protein 1, JP-45, JP45

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.25 mg/mL (determined by Bradford assay)

Purity

> 90% by SDS-PAGE

Molecular Weight

38 kDa (354aa) confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)

Additionnal Information

JSRP1, Junctional sarcoplasmic reticulum protein 1, JP-45, JP45, ATGP2339-10 µg, ATGP2339-20 µg, ATGP2339-50 µg, ATGP2339-100 µg, ATGP2339-250 µg, ATGP2339-500 µg, ATGP2339-1 mg, ATGP2339-10, ATGP2339-20, ATGP2339-50, ATGP2339-100, ATGP2339-250, ATGP2339-500, ATGP2339-1

References & Citations

Yasuda T, Delbono O, et al. (2013) . Hum Mutat. 34 (1) :184-90.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol

Scientific Category

Other

NCBI Accession Number

NP_653217.1

Uniprot Accession Number

Q96MG2

Species

Human

AA Sequence

MSMTTRA WEELDGGLGS CQALEDHSAL AETQEDRASA TPRLADSGSV PHDSQVAEGP SVDTRPKKME KEPAARGTPG TGKERLKAGA SPRSVPARKK AQTAPPLQPP PPPPALSEEL PWGDLSLNKC LVLASLVALL GSAFQLCRDA VPGEAALQAR VPEPWVPPSS APREPSSPLP KFEAQAPPSA PPAPRAEAEV RPKIPGSREA AENDEEEPGE ATGEAVREDR VTLADRGPKE RPRREGKPRK EKPRKEERPK KERPRKEERP RAAREPREAL PQRWESREGG HRPWARDSRD AEPRKKQAWV SPRRPDEEQR PGSRQKLRAG KGRD