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Recombinant human Epigen protein

EPGN is a member of the epidermal growth factor family. Members of this family are ligands for the epidermal growth factor receptor and play a role in cell survival, proliferation and migration. This protein has been reported to have high mitogenic activity but low affinity for its receptor. Expression of this transcript and protein has been reported in cancer specimens of the breast, bladder, and prostate. Alternative splicing results in multiple transcript variants. Recombinant human EPGN, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Epigen isoform 1 precursor, ALGV3072, EPG, PRO9904

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE, Denatured

Concentration

1 mg/mL (determined by Bradford assay)

Purity

> 90% by SDS-PAGE

Molecular Weight

12.1 kDa (111aa)

Additionnal Information

Epigen, epigen isoform 1 precursor, ALGV3072, EPG, PRO9904, ATGP2332-10 µg, ATGP2332-20 µg, ATGP2332-50 µg, ATGP2332-100 µg, ATGP2332-250 µg, ATGP2332-500 µg, ATGP2332-1 mg, ATGP2332-10, ATGP2332-20, ATGP2332-50, ATGP2332-100, ATGP2332-250, ATGP2332-500, ATGP2332-1

References & Citations

Kennedy, R.B., et al. (2012) Hum. Genet. 131 (9), 1403-1421; ; Wilson, K.J., et al. (2012) Growth Factors 30 (2), 107-116;

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.4M uREA, 10% glycerol

Scientific Category

Hormones & Cytokines

NCBI Accession Number

NP_001257918

Uniprot Accession Number

Q6UW88

Species

Human

AA Sequence

MGSSHHHHHH SSGLVPRGSH MGSAAVTVTP PITAQQGNWT VNKTEADNIE GPIALKFSHL CLEDHNSYCI NGACAFHHEL EKAICRCFTG YTGERCEHLT LTSYAVDSYE K

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