Recombinant human Fucosyltransferase 3/FUT3 protein
Fucosyltransferase 3, also known as FuT3, may catalyze alpha-1, 3 and alpha-1, 4 glycosidic linkages involved in the expression of Vim-2, Lewis A, Lewis B, sialyl Lewis X and Lewis X/SSEA-1 antigens. This protein may be involved in blood group Lewis determination; Lewis-positive (Le+) individuals have an active enzyme while Lewis-negative (Le-) individuals have an inactive enzyme. Also acts on the corresponding 1, 4-galactosyl derivative, forming 1, 3-L-fucosyl links. Recombinant human FuT3 protein, fused to His-tag at N-terminus, was expressed in E. coli.
Product Specifications
Product Name Alternative
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE, Denatured
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 80% by SDS-PAGE
Molecular Weight
40.6 kDa (350aa)
Additionnal Information
References & Citations
Cameron H.S., et al. (1995) J. Biol. Chem. 270:20112-20122; ; Nishihara S., et al. (1993) Biochem. Biophys. Res. Commun. 196:624-631;
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol
Scientific Category
Cardiovascular
NCBI Accession Number
NP_001091110
Uniprot Accession Number
P21217
Species
Human
AA Sequence
Frequently Asked Questions
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