Recombinant human TADA3 protein

Transcriptional adapter 3 isoform a, also known as TATD3, is a subunit of 2 histone acetyltransferase complexes. TATD3 is a transcriptional activator adaptor and has been found to be part of the PCAF histone acetylase complex. In addition, it associates with the tumor suppressor protein p53 and is required for full activity of p53 and p53-mediated apoptosis. Recombinant human TATD3 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Transcriptional adapter 3 isoform a, Transcriptional adapter 3 isoform a, ADA3, hADA3, NGG1, TADA3L

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.5 mg/mL (determined by Bradford assay)

Purity

> 80% by SDS-PAGE

Molecular Weight

51.3 kDa (455aa)

Additionnal Information

TADA3, Transcriptional adapter 3 isoform a, Transcriptional adapter 3 isoform a, ADA3, hADA3, NGG1, TADA3L, ATGP2312-10 µg, ATGP2312-20 µg, ATGP2312-50 µg, ATGP2312-100 µg, ATGP2312-250 µg, ATGP2312-500 µg, ATGP2312-1 mg, ATGP2312-10, ATGP2312-20, ATGP2312-50, ATGP2312-100, ATGP2312-250, ATGP2312-500, ATGP2312-1

References & Citations

Li CW., et al. (2010) Nucleic Acids Res. 38 (16) :5291-303.; ; Hu Y., et al. (2009) Cancer Invest. 27 (3) :298-306.;

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 50% glycerol, 2mM DTT

Scientific Category

Epigenomics (Transcription & Translation)

NCBI Accession Number

NP_006345

Uniprot Accession Number

O75528

Species

Human

AA Sequence

MGSSHHHHHH SSGLVPRGSH MGSMSELKDC PLQFHDFKSV DHLKVCPRYT AVLARSEDDG IGIEELDTLQ LELETLLSSA SRRLRVLEAE TQILTDWQDK KGDRRFLKLG RDHELGAPPK HGKPKKQKLE GKAGHGPGPG PGRPKSKNLQ PKIQEYEFTD DPIDVPRIPK NDAPNRFWAS VEPYCADITS EEVRTLEELL KPPEDEAEHY KIPPLGKHYS QRWAQEDLLE EQKDGARAAA VADKKKGLMG PLTELDTKDV DALLKKSEAQ HEQPEDGCPF GALTQRLLQA LVEENIISPM EDSPIPDMSG KESGADGAST SPRNQNKPFS VPHTKSLESR IKEELIAQGL LESEDRPAED SEDEVLAELR KRQAELKALS AHNRTKKHDL LRLAKEEVSR QELRQRVRMA DNEVMDAFRK IMAARQKKRT PTKKEKDQAW KTLKERESIL KLLDG