Recombinant human Follistatin-like 1 protein

FSTL1 is a protein with similarity to follistatin, an activin-binding protein. It contains an FS module, a follistatin-like sequence containing 10 conserved cysteine residues. This protein is thought to be an autoantigen associated with rheumatoid arthritis. Recombinant human FSTL1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Follistatin-related protein 1, FRP, FSL1

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.5 mg/mL (determined by Bradford assay)

Purity

> 90% by SDS-PAGE

Molecular Weight

34.9 kDa (309aa) confirmed by MALDI-TOF

Additionnal Information

Follistatin-like1, follistatin-related protein 1, FRP, FSL1, ATGP2302-10 µg, ATGP2302-20 µg, ATGP2302-50 µg, ATGP2302-100 µg, ATGP2302-250 µg, ATGP2302-500 µg, ATGP2302-1 mg, ATGP2302-10, ATGP2302-20, ATGP2302-50, ATGP2302-100, ATGP2302-250, ATGP2302-500, ATGP2302-1

References & Citations

Tanaka M., et al (1998) . Int. Immunol. 10:1305-1314; ; Ehara Y., et al (2004) . Clin. Exp. Rheumatol. 22:707-712

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 20% glycerol, 1mM DTT

Scientific Category

Cardiovascular

NCBI Accession Number

NP_009016.1

Uniprot Accession Number

Q12841

Species

Human

AA Sequence

EEELRSKSK ICANVFCGAG RECAVTEKGE PTCLCIEQCK PHKRPVCGSN GKTYLNHCEL HRDACLTGSK IQVDYDGHCK EKKSVSPSAS PVVCYQSNRD ELRRRIIQWL EAEIIPDGWF SKGSNYSEIL DKYFKNFDNG DSRLDSSEFL KFVEQNETAI NITTYPDQEN NKLLRGLCVD ALIELSDENA DWKLSFQEFL KCLNPSFNPP EKKCALEDET YADGAETEVD CNRCVCACGN WVCTAMTCDG KNQKGAQTQT EEEMTRYVQE LQKHQETAEK TKRVSTKEI