Recombinant human MRPS2 protein
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. MRPS2 is a 28S subunit protein that belongs to the ribosomal protein S2 family. Recombinant human MRPS2 protein, fused to His-tag at N-terminus, was expressed in E. coli.
Product Specifications
Product Name Alternative
Mitochondrial ribosomal protein S2, CGI-91, MRP-S2, S2mt
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 85% by SDS-PAGE
Molecular Weight
35.6 kDa (319aa)
Additionnal Information
References & Citations
Suzuki T., et al (2001) . J. Biol. Chem. 276:33181-33195; ; Koc E.C., et al (2001) . J. Biol. Chem. 276:19363-19374
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol
Scientific Category
Epigenomics (Transcription & Translation)
NCBI Accession Number
NP_057118
Uniprot Accession Number
Q9Y399
Species
Human
AA Sequence
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