Recombinant human MRPS2 protein

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. MRPS2 is a 28S subunit protein that belongs to the ribosomal protein S2 family. Recombinant human MRPS2 protein, fused to His-tag at N-terminus, was expressed in E. coli.

Product Specifications

Product Name Alternative

Mitochondrial ribosomal protein S2, CGI-91, MRP-S2, S2mt

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

1 mg/mL (determined by Bradford assay)

Purity

> 85% by SDS-PAGE

Molecular Weight

35.6 kDa (319aa)

Additionnal Information

MRPS2, Mitochondrial ribosomal protein S2, CGI-91, MRP-S2, S2mt, ATGP2301-10 µg, ATGP2301-20 µg, ATGP2301-50 µg, ATGP2301-100 µg, ATGP2301-250 µg, ATGP2301-500 µg, ATGP2301-1 mg, ATGP2301-10, ATGP2301-20, ATGP2301-50, ATGP2301-100, ATGP2301-250, ATGP2301-500, ATGP2301-1

References & Citations

Suzuki T., et al (2001) . J. Biol. Chem. 276:33181-33195; ; Koc E.C., et al (2001) . J. Biol. Chem. 276:19363-19374

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol

Scientific Category

Epigenomics (Transcription & Translation)

NCBI Accession Number

NP_057118

Uniprot Accession Number

Q9Y399

Species

Human

AA Sequence

MGSSHHHHHH SSGLVPRGSH MGSMATSSAA LPRILGAGAR APSRWLGFLG KATPRPARPS RRTLGSATAL MIRESEDSTD FNDKILNEPL KHSDFFNVKE LFSVRSLFDA RVHLGHKAGC RHRFMEPYIF GSRLDHDIID LEQTATHLQL ALNFTAHMAY RKGIILFISR NRQFSYLIEN MARDCGEYAH TRYFRGGMLT NARLLFGPTV RLPDLIIFLH TLNNIFEPHV AVRDAAKMNI PTVGIVDTNC NPCLITYPVP GNDDSPLAVH LYCRLFQTAI TRAKEKRQQV EALYRLQGQK EPGDQGPAHP PGADMSHSL