Recombinant human TSSK2 protein

TSSK2 is a testis-specific serine/threonine-protein kinase required during spermatid development. This protein phosphorylates TSKS at 'Ser-288' and SPAG16. TSSK2 involved in the late stages of spermatogenesis, during the reconstruction of the cytoplasm. During spermatogenesis, it is required for the transformation of a ring-shaped structure around the base of the flagellum originating from the chromatoid body. Recombinant human TSSK2 protein, fused to His-tag at N-terminus, was expressed in E. coli.

Product Specifications

Product Name Alternative

Testis-specific serine/threonine-protein kinase 2, DGS-G, SPOGA2, STK22B, TSK2

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE, Denatured

Concentration

0.25 mg/mL (determined by Bradford assay)

Purity

> 85% by SDS-PAGE

Molecular Weight

43 kDa (381aa)

Additionnal Information

TSSK2, Testis-specific serine/threonine-protein kinase 2, DGS-G, SPOGA2, STK22B, TSK2, ATGP2293-10 µg, ATGP2293-20 µg, ATGP2293-50 µg, ATGP2293-100 µg, ATGP2293-250 µg, ATGP2293-500 µg, ATGP2293-1 mg, ATGP2293-10, ATGP2293-20, ATGP2293-50, ATGP2293-100, ATGP2293-250, ATGP2293-500, ATGP2293-1

References & Citations

Kueng P, Nikolova Z, et al. (1997) . J Cell Biol. 139 (7) :1851-9.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol

Scientific Category

Signal Transduction

NCBI Accession Number

NP_443732

Uniprot Accession Number

Q96PF2

Species

Human

AA Sequence

MGSSHHHHHH SSGLVPRGSH MGSMDDATVL RKKGYIVGIN LGKGSYAKVK SAYSERLKFN VAVKIIDRKK TPTDFVERFL PREMDILATV NHGSIIKTYE IFETSDGRIY IIMELGVQGD LLEFIKCQGA LHEDVARKMF RQLSSAVKYC HDLDIVHRDL KCENLLLDKD FNIKLSDFGF SKRCLRDSNG RIILSKTFCG SAAYAAPEVL QSIPYQPKVY DIWSLGVILY IMVCGSMPYD DSDIRKMLRI QKEHRVDFPR SKNLTCECKD LIYRMLQPDV SQRLHIDEIL SHSWLQPPKP KATSSASFKR EGEGKYRAEC KLDTKTGLRP DHRPDHKLGA KTQHRLLVVP ENENRMEDRL AETSRAKDHH ISGAEVGKAS T