Recombinant human HEPACAM2 protein

HEPACAM2 is required during prometaphase for centrosome maturation. Following poly-ADP-ribosylation (PARsylation) by TNKS, this protein translocates from the Golgi apparatus to mitotic centrosomes and plays a key role in the formation of robust microtubules for prompt movement of chromosomes. Recombinant human HEPACAM2 protein, fused to His-tag at N-terminus, was expressed in E. coli.

Product Specifications

Product Name Alternative

HEPACAM family member 2 isoform 1, MIKI

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE, Denatured

Concentration

1 mg/mL (determined by Bradford assay)

Purity

> 85% by SDS-PAGE

Molecular Weight

37.9 kDa (343aa)

Additionnal Information

HEPACAM2, HEPACAM family member 2 isoform 1, MIKI, ATGP2287-10 µg, ATGP2287-20 µg, ATGP2287-50 µg, ATGP2287-100 µg, ATGP2287-250 µg, ATGP2287-500 µg, ATGP2287-1 mg, ATGP2287-10, ATGP2287-20, ATGP2287-50, ATGP2287-100, ATGP2287-250, ATGP2287-500, ATGP2287-1

References & Citations

Klopfleisch R., et al. (2010) BMC Vet Res. 15:6-15.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol

Scientific Category

Cell Cycle

NCBI Accession Number

NP_001034461

Uniprot Accession Number

A8MVW5

Species

Human

AA Sequence

MGSSHHHHHH SSGLVPRGSH MGSLKVTVPS HTVHGVRGQA LYLPVHYGFH TPASDIQIIW LFERPHTMPK YLLGSVNKSV VPDLEYQHKF TMMPPNASLL INPLQFPDEG NYIVKVNIQG NGTLSASQKI QVTVDDPVTK PVVQIHPPSG AVEYVGNMTL TCHVEGGTRL AYQWLKNGRP VHTSSTYSFS PQNNTLHIAP VTKEDIGNYS CLVRNPVSEM ESDIIMPIIY YGPYGLQVNS DKGLKVGEVF TVDLGEAILF DCSADSHPPN TYSWIRRTDN TTYIIKHGPR LEVASEKVAQ KTMDYVCCAY NNITGRQDET HFTVIITSVG LEKLAQKGKS LSP