Recombinant human HEPACAM2 protein
HEPACAM2 is required during prometaphase for centrosome maturation. Following poly-ADP-ribosylation (PARsylation) by TNKS, this protein translocates from the Golgi apparatus to mitotic centrosomes and plays a key role in the formation of robust microtubules for prompt movement of chromosomes. Recombinant human HEPACAM2 protein, fused to His-tag at N-terminus, was expressed in E. coli.
Product Specifications
Product Name Alternative
HEPACAM family member 2 isoform 1, MIKI
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE, Denatured
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 85% by SDS-PAGE
Molecular Weight
37.9 kDa (343aa)
Additionnal Information
References & Citations
Klopfleisch R., et al. (2010) BMC Vet Res. 15:6-15.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol
Scientific Category
Cell Cycle
NCBI Accession Number
NP_001034461
Uniprot Accession Number
A8MVW5
Species
Human
AA Sequence
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