Recombinant human SCN3B protein

Voltage-gated sodium channels are transmembrane glycoprotein complexes composed of a large alpha subunit and one or more regulatory beta subunits. They are responsible for the generation and propagation of action potentials in neurons and muscle. SCN3B is one member of the sodium channel beta subunit gene family, and influences the inactivation kinetics of the sodium channel. Two alternatively spliced variants, encoding the same protein, have been identified. Recombinant human SCN3B protein, fused to His-tag at N-terminus, was expressed in E. coli.

Product Specifications

Product Name Alternative

Sodium channel subunit beta-3 precursor, Sodium channel, voltage-gated, type III, beta subunit, HSA243396, SCNB3

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.5 mg/mL (determined by Bradford assay)

Purity

> 90% by SDS-PAGE

Molecular Weight

18.1 kDa (160aa)

Additionnal Information

SCN3B, Sodium channel subunit beta-3 precursor, Sodium channel, voltage-gated, type III, beta subunit, HSA243396, SCNB3, ATGP2285-10 µg, ATGP2285-20 µg, ATGP2285-50 µg, ATGP2285-100 µg, ATGP2285-250 µg, ATGP2285-500 µg, ATGP2285-1 mg, ATGP2285-10, ATGP2285-20, ATGP2285-50, ATGP2285-100, ATGP2285-250, ATGP2285-500, ATGP2285-1

References & Citations

Morgan K. et al. (2000) . u.S.A. 97:2308-2313 ; ; Wiemann S et al. (2001) . Genome Res. 11:422-435

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol

Scientific Category

Neuroscience

NCBI Accession Number

NP_060870

Uniprot Accession Number

Q9NY72

Species

Human

AA Sequence

FPVCVEV PSETEAVQGN PMKLRCISCM KREEVEATTV VEWFYRPEGG KDFLIYEYRN GHQEVESPFQ GRLQWNGSKD LQDVSITVLN VTLNDSGLYT CNVSREFEFE AHRPFVKTTR LIPLRVTEEA GEDFTSVVSE