Recombinant human DNA polymerase delta subunit 4/POLD4 protein

POLD4 is the smallest subunit of DNA polymerase delta. DNA polymerase delta possesses both polymerase and 3' to 5' exonuclease activity and plays a critical role in DNA replication and repair. The protein enhances the activity of DNA polymerase delta and plays a role in fork repair and stabilization through interactions with the DNA helicase Bloom syndrome protein. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Recombinant human POLD4 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

DNA polymerase delta 4 accessory subunit, DNA polymerase delta smallest subunit p12, DNA polymerase delta subunit p12

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.25 mg/mL (determined by Bradford assay)

Purity

> 90% by SDS-PAGE

Molecular Weight

14.8 kDa (130aa) confirmed by MALDI-TOF

Additionnal Information

POLD4, DNA polymerase delta subunit 4, p12, POLDS, ATGP2282-10 µg, ATGP2282-20 µg, ATGP2282-50 µg, ATGP2282-100 µg, ATGP2282-250 µg, ATGP2282-500 µg, ATGP2282-1 mg, ATGP2282-10, ATGP2282-20, ATGP2282-50, ATGP2282-100, ATGP2282-250, ATGP2282-500, ATGP2282-1